Biochemistry: From Molecules to Metabolism
Explore the building blocks of life, enzyme function, and complex metabolic pathways in this comprehensive biochemistry course.
Explore the building blocks of life, enzyme function, and complex metabolic pathways in this comprehensive biochemistry course.
Dive into the fascinating world of biochemistry with this comprehensive course from Harvard. Starting from the basic building blocks of life, you'll journey through the complexities of cellular metabolism and protein function. The course integrates macromolecular structure studies with biochemical approaches to cellular function, providing a solid foundation in biochemical principles. You'll explore enzyme kinetics, major metabolic pathways, and their intricate regulatory networks. Using examples from simple cells to complex tissues, you'll gain insights into the progression of metabolic complexity. The course emphasizes practical skills, including protein structure visualization using PyMOL and the development of problem-solving abilities applicable across life sciences. By the end, you'll have a deep understanding of how biochemical processes integrate within cells, tissues, and organisms, preparing you for advanced studies or research in biology and medicine.
4.6
(43 ratings)
3,88,212 already enrolled
Instructors:
Alain Viel
Rachelle Gaudet
English
English
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What you'll learn
Understand the structure and function of life's chemical building blocks
Visualize and analyze protein structures using PyMOL software
Explain the central role of enzymes in biological catalysis
Describe the primary metabolic pathways that drive cellular function
Analyze the regulatory mechanisms controlling cellular metabolism
Integrate biochemical processes across cellular, tissue, and organismal levels
Skills you'll gain
This course includes:
PreRecorded video
Graded assignments, exams
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Limited Access access
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Module Description
This comprehensive biochemistry course offers an in-depth exploration of life's molecular foundations. Beginning with the structure and function of biological molecules, the curriculum progresses to complex metabolic pathways and their regulation. Key topics include enzyme kinetics, protein structure and function, and the intricate networks of cellular metabolism. The course uses a comparative approach, examining biochemical processes in various biological contexts, from simple red blood cells to complex tissues like muscle and liver. This method illuminates the progression of metabolic complexity across different biological systems. Practical skills are emphasized, including the use of PyMOL for protein structure visualization and the development of analytical problem-solving skills applicable to broader life science contexts. The integration of biochemical processes at cellular, tissue, and organismal levels provides students with a holistic understanding of biochemistry's role in biological function.
Fee Structure
Instructors
Alain Viel
1 Course
Senior Lecturer, Department of Molecular and Cellular Biology at Harvard University
Alain Viel is the Director of Undergraduate Research and a Senior Lecturer in the Department of Molecular and Cellular Biology at Harvard University. He holds a PhD in Molecular and Cellular Biology of Development from Pierre and Marie Curie University in Paris, France, and completed his postdoctoral research at Harvard. Specializing in biochemistry, cell biology, molecular biology, and biology education, Dr. Viel teaches research-based and foundational courses in molecular biology and biochemistry. He is a founding member of BioVisions, a collaborative initiative focused on science visualization that brings together scientists, educators, students, and multimedia professionals. Dr. Viel is also the co-author of the acclaimed animation series “The Inner Life of the Cell,” and has contributed to other major works such as “Powering the Cell: Mitochondria” and “Protein Packing,” all of which have advanced the public understanding of complex biological processes.
Rachelle Gaudet
1 Course
Professor of Molecular and Cellular Biology at Harvard University
Rachelle Gaudet is a Professor of Molecular and Cellular Biology at Harvard University, specializing in biochemistry, structural biology, ion channels and transporters, and antigen processing. She earned her B.Sc. in Biochemistry from Université de Montréal, her Ph.D. in Molecular Biophysics and Biochemistry from Yale University, and completed her postdoctoral work at Harvard. Since joining Harvard’s faculty in 2002, Dr. Gaudet has conducted pioneering research in the structural biology of membrane proteins, using x-ray crystallography and biochemistry to reveal the molecular mechanisms underlying transport and signaling proteins involved in immunity, neuronal development, pain perception, and hearing. She teaches biochemistry and physical chemistry for the life sciences and is the author of influential works such as “Structure of a force-conveying cadherin bond essential for inner-ear mechanotransduction” (Nature, 2012), “The ankyrin repeats of TRPV1 bind multiple ligands and modulate channel sensitivity” (Neuron, 2007), and “Distinct structural and functional properties of the ATPase sites in an asymmetric ABC transporter” (Molecular Cell, 2006).
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