The exposome: cracking the science about what makes us sick
Explore how environmental factors and exposures throughout life influence health and disease through innovative research approaches.
Explore how environmental factors and exposures throughout life influence health and disease through innovative research approaches.
This comprehensive course examines the exposome concept - the totality of environmental exposures affecting human health. Students learn about external and internal exposome measurements, data analysis methods, and applications in disease research. The curriculum combines insights from public health, environmental science, and data analytics to understand non-genetic drivers of health outcomes.
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What you'll learn
Understand exposome concept and importance
Analyze environmental exposure data
Evaluate health outcome associations
Apply data science techniques
Assess exposure measurement methods
Integrate multiple scientific approaches
Skills you'll gain
This course includes:
38 Minutes PreRecorded video
4 assignments
Access on Mobile, Tablet, Desktop
Batch access
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There are 6 modules in this course
This course provides an in-depth exploration of exposome research through six comprehensive modules. Students learn about external and internal exposure assessment, methodological approaches, and data analysis techniques. The curriculum emphasizes transdisciplinary perspectives and emerging research methods in environmental health science.
Introduction to the Exposome concept
Module 1 · 2 Hours to complete
The transformative power of Exposome approaches: using the example of cardiovascular disease research
Module 2 · 2 Hours to complete
The external Exposome: methodological approaches
Module 3 · 2 Hours to complete
The internal Exposome: methodological approaches
Module 4 · 2 Hours to complete
Data science steps for analysing Exposome data
Module 5 · 2 Hours to complete
Future perspectives & the next generation of studies
Module 6 · 3 Hours to complete
Fee Structure
Instructors
Clinical Epidemiology Expert and Global Health Leader
Dr. Diederick (Rick) Grobbee serves as Professor of Clinical Epidemiology at Utrecht University Medical Center and Distinguished University Professor of International Health Sciences and Global Health. His academic credentials include an MD from Utrecht University and a Ph.D. in Epidemiology from Erasmus University Rotterdam. Through his Coursera courses in epidemiology and clinical research, he helps students understand principles of medical research and global health. As founder of the Julius Center in 1996, he established one of the world's leading institutions for clinical epidemiology. His research focuses on cardiovascular disease prevention and treatment, having authored over 1,300 scientific papers and supervised more than 150 Ph.D. fellows. His contributions earned him fellowship in the Royal Dutch Academy of Sciences and knighthood in the Order of the Dutch Lion. Currently serving as Editor-in-Chief of Global Heart and Chief Scientific Officer of Julius Clinical Research, he continues to advance clinical research and global health initiatives while directing the MSc program in Epidemiology at Utrecht University.
Professor of Environmental Epidemiology
Roel Vermeulen is a Professor of Environmental Epidemiology and Exposome Science at Utrecht University and the University Medical Center Utrecht. He specializes in environmental risk factors for non-communicable diseases, integrating epidemiology, high-quality exposure assessment, and molecular biology through multidisciplinary research. Vermeulen leads prominent projects like the Dutch Exposome-NL consortium, the European EXPANSE project targeting urban exposomes, and the Utrecht Exposome Hub. His work focuses on quantifying external and internal exposomes—comprehensive environmental exposures influencing health throughout life stages—and their impacts on diseases such as cardiovascular conditions and diabetes. He has significant roles in European research networks and has contributed extensively to advancing exposome science globally.
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