Chemical Biology: Bridging Chemistry and Life Sciences
Explore the interface of chemistry and biology, mastering techniques to study and manipulate biological processes at the molecular level.
Explore the interface of chemistry and biology, mastering techniques to study and manipulate biological processes at the molecular level.
This comprehensive course delves into the exciting field of chemical biology, examining how chemical tools and approaches can be used to understand and manipulate biological systems. Designed for intermediate-level learners with a background in chemistry, biology, and physics, the course covers key topics such as fluorescence microscopy, protein labeling, membrane tension measurement, and large-scale screening methods. Through six engaging modules, students will gain insights into cutting-edge techniques used to study cellular processes in real-time. The course balances theoretical concepts with practical applications, emphasizing the interdisciplinary nature of chemical biology and its potential to address critical questions in life sciences.
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What you'll learn
Understand the fundamental principles and applications of chemical biology
Master fluorescence-based techniques for studying cellular processes in real-time
Learn protein labeling strategies and fusion protein design for biological studies
Gain insights into membrane biology and techniques for measuring membrane tension
Understand light-induced chemistry for controlling biological processes
Explore large-scale screening methods for drug discovery and target identification
Skills you'll gain
This course includes:
5.7 Hours PreRecorded video
25 quizzes
Access on Mobile, Tablet, Desktop
FullTime access
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There are 6 modules in this course
This course provides a comprehensive exploration of chemical biology, focusing on the intersection of chemistry, biology, and physics to study and manipulate biological systems at the molecular level. The curriculum is structured to build a strong foundation in chemical biology concepts and techniques, starting with fundamental principles and progressing to advanced applications. Students will learn about fluorescence-based techniques, protein labeling strategies, membrane biology, and large-scale screening methods. The course emphasizes both theoretical understanding and practical applications, with modules covering topics such as fluorophore design, TIRF microscopy, membrane tension measurement, and library synthesis for drug discovery. By the end of the course, learners will have gained a deep understanding of how chemical tools can be used to probe and control biological processes, preparing them for cutting-edge research in life sciences.
Welcome to Chemical Biology: Concepts and techniques
Module 1 · 3 Hours to complete
The Devil is in the Minutest Detail
Module 2 · 2 Hours to complete
A ruler over time and space! Fluorescent assays to measure complex parameters in real time
Module 3 · 3 Hours to complete
Putting proteins to work for us
Module 4 · 4 Hours to complete
Making light work of it on a larger and larger scale
Module 5 · 3 Hours to complete
Casting wide your net
Module 6 · 2 Hours to complete
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Instructors
Prof. Dr.
Robbie J. Loewith was born in Hamilton, Ontario, Canada. He studied biochemistry, molecular biology, and genetics at the University of Guelph before earning his PhD under the supervision of Prof. Dallan Young at the University of Calgary. Following this, he completed postdoctoral work at the University of Basel Biozentrum with Prof. Michael Hall, where he discovered the two Target Of Rapamycin Complexes. In 2005, he started his independent research group in the Department of Molecular Biology at the University of Geneva and became a full professor in 2015.
Dr
Marcus J. C. Long was born in East Yorkshire. He was a chemistry scholar at New College, Oxford University, and completed his PhD in biochemistry under the supervision of Prof. Liz Hedstrom at Brandeis University as a Howard Hughes Medical Institute International Fellow. He then undertook postdoctoral work at Cornell University with Prof. Yimon Aye. Throughout his career, he has collaborated with over 10 laboratories worldwide.
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