Liliane Tenenbaum

Liliane Tenenbaum is a Senior Lecturer and Group Leader at the Laboratory of Neurotherapies and Neuromodulation, University of Lausanne. Her research focuses on developing neuroprotective gene therapies for Parkinson's disease (PD). Tenenbaum's work explores the potential of neurotrophic factors, particularly Glial Cell Line-Derived Neurotrophic Factor (GDNF), in treating PD. She has made significant contributions to understanding the complex relationship between GDNF dosage, delivery methods, and therapeutic outcomes. Her studies have revealed that while GDNF can provide neuroprotection and improve motor symptoms in animal models, its efficacy depends on precise dosing and delivery strategies. Tenenbaum's research has highlighted the challenges of translating promising preclinical results into effective treatments for PD patients, emphasizing the need for carefully regulated gene therapy approaches. Her work continues to advance the field of neurodegenerative disease treatment, aiming to develop the first disease-modifying therapy for Parkinson's disease.