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Finding Mutations in DNA and Proteins (Bioinformatics VI)
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Finding Mutations in DNA and Proteins (Bioinformatics VI)

This course is part of Bioinformatics Specialization.

Course Cost

Free course

Intermediate

Skill Level

21 Hours

Self-paced lessons

This course cannot be purchased separately - to access the complete learning experience, graded assignments, and earn certificates, you'll need to enroll in the full Bioinformatics Specialization program. You can audit this specific course for free to explore the content, which includes access to course materials and lectures. This allows you to learn at your own pace without any financial commitment.

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4.7

15,813 Enrolled

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English

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olive-leaves-logo

4.7

15,813 Enrolled

olive-leaves-logo

English

What you'll learn

  • Implement efficient DNA read mapping algorithms

  • Master the Burrows-Wheeler transform for pattern matching

  • Develop solutions for inexact pattern matching

  • Apply hidden Markov models to sequence analysis

  • Analyze highly mutated protein sequences

  • Use profile HMMs for protein classification

Skills you'll gain

DNA Sequencing
Pattern Matching
Hidden Markov Models
Protein Analysis
Burrows-Wheeler Transform
Sequence Alignment
Mutation Detection
Bioinformatics Algorithms
HIV Analysis

This course includes:

2.5 Hours PreRecorded video

3 assignments, 1 peer review

Access on Mobile, Tablet, Desktop

FullTime access

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There are 6 modules in this course

This advanced bioinformatics course focuses on computational methods for finding mutations in DNA and proteins. The first half covers efficient algorithms for mapping DNA fragments to reference genomes using combinatorial pattern matching and the Burrows-Wheeler transform. The second half explores hidden Markov models for identifying protein functions, particularly in rapidly mutating sequences like HIV. Students learn both theoretical foundations and practical applications of these advanced bioinformatics tools.

Introduction to Read Mapping

Module 1 · 4 Hours to complete

The Burrows-Wheeler Transform

Module 2 · 4 Hours to complete

Speeding Up Burrows-Wheeler Read Mapping

Module 3 · 3 Hours to complete

Introduction to Hidden Markov Models

Module 4 · 3 Hours to complete

Profile HMMs for Sequence Alignment

Module 5 · 4 Hours to complete

Bioinformatics Application Challenge

Module 6 · 3 Hours to complete

Fee Structure

Individual course purchase is not available - to enroll in this course with a certificate, you need to purchase the complete Professional Certificate Course. For enrollment and detailed fee structure, visit the following: Bioinformatics Specialization

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Faculties

These are the expert instructors who will be teaching you throughout the course. With a wealth of knowledge and real-world experience, they're here to guide, inspire, and support you every step of the way. Get to know the people who will help you reach your learning goals and make the most of your journey.

Finding Mutations in DNA and Proteins (Bioinformatics VI)

Intermediate

Skill Level

21 Hours

Self-paced lessons

Course Cost

Free course

Completion

CERTIFICATE

Frequently asked Questions

Below are some of the most commonly asked questions about this course. We aim to provide clear and concise answers to help you better understand the course content, structure, and any other relevant information. If you have any additional questions or if your question is not listed here, please don't hesitate to reach out to our support team for further assistance.