Immune Defense: T-Cells & Cell Signaling

This module covers the complement system, including overview, terminology, MAC activation, and the classical, alternative, and lectin pathways. It explores the mechanisms and consequences of complement activation in immune response.

This module explores MHC genes, haplotypes, protein structure, peptide binding, genetic expression, and disease relationships. It covers both classical and non-classical alleles and their roles in immune function.

This module focuses on T cell antigen recognition, self-MHC restriction, cytosolic and exogenous pathways, and comparative analysis of antigen processing mechanisms.

This module covers T-cell receptor structure, genes, gene rearrangement for both αβ and γδ genes, diversity constraints, receptor complex, and alloreactivity.

This module examines T-cell development in the thymus, including double negative transitions, positive and negative selection, CD4+ varieties, and activation processes.

This module explores information transfer, fundamental and contributory signals, common signaling themes, TH subset determination and signaling, and clinical applications.

This concluding module provides a final assessment of the course material and includes a farewell message and end-of-course survey.