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Metabolite Signaling: Fundamentals and Applications
Explore how small molecules regulate cellular functions. Learn the biochemical basis of metabolite-mediated cell signaling in health and disease.
Explore how small molecules regulate cellular functions. Learn the biochemical basis of metabolite-mediated cell signaling in health and disease.
This course offers a comprehensive introduction to the signaling actions of small molecules in cellular processes. Over six weeks, students will delve into the fundamental principles of metabolite-mediated cell signaling, exploring how these small molecules interact with proteins to regulate various biological functions. The curriculum covers the biochemical basis of metabolite actions, emphasizing their roles in energy metabolism, macromolecular biosynthesis, and degradation. Students will learn about the significance of metabolite-protein interactions in living cells and their impact on target protein functions and activities. The course relates these concepts to human health and disease, including cancer and inflammation, providing real-world context for the material. By examining specific examples of endogenous small molecule interactions with target proteins, students will gain a deeper understanding of complex cellular signaling systems. The course also touches on intriguing topics such as the action of noxious gases in controlling blood pressure and the influence of gut microbiota on the body, offering a broad perspective on the field.
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What you'll learn
Understand the concept of metabolites and their roles in cellular processes
Explore the biochemical basis of metabolite-mediated cell signaling
Learn about different types of molecular interactions in cells
Analyze the impact of metabolite-protein interactions on cellular functions
Examine the role of small molecules in energy metabolism and gene expression
Investigate the connection between metabolite signaling and human diseases like cancer
Skills you'll gain
This course includes:
361 Minutes PreRecorded video
7 quizzes
Access on Mobile, Tablet, Desktop
FullTime access
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There are 7 modules in this course
This course provides a solid foundation in the emerging field of metabolite-mediated cell signaling. It explores the crucial roles of small molecules, or metabolites, in regulating cellular functions and their impact on human health and disease. The curriculum is structured to build a comprehensive understanding of how metabolites interact with proteins to influence various biological processes. Students will learn about the biochemical basis of metabolite actions, their roles in energy metabolism, and their significance in macromolecular biosynthesis and degradation. The course emphasizes the importance of metabolite-protein interactions in living cells and their effects on target protein functions and activities. Throughout the six weeks, students will examine specific examples of how endogenous small molecules interact with target proteins and control their functions, with applications to major health issues such as cancer and inflammation. The course also covers intriguing topics like the action of noxious gases in blood pressure regulation and the influence of gut microbiota on the body, providing a broad perspective on the complexity of cellular signaling systems.
Week 1
Module 1 · 1 Hours to complete
Week 2
Module 2 · 1 Hours to complete
Week 3
Module 3 · 1 Hours to complete
Week 4
Module 4 · 1 Hours to complete
Week 5
Module 5 · 1 Hours to complete
Week 6
Module 6 · 1 Hours to complete
Final exam
Module 7 · 40 Minutes to complete
Fee Structure
Payment options
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Instructor
Exploring Inositol Phosphate Metabolism in Mammalian Biology
Seyun Kim is an associate professor in the Department of Biological Sciences at KAIST in Korea, where he focuses on the biochemical and genetic mechanisms connecting inositol phosphate metabolism to metabolic homeostasis and signaling events in mammals. He earned his Ph.D. in Biological Chemistry from Johns Hopkins University School of Medicine and is dedicated to advancing the understanding of how these metabolic processes regulate physiological functions.
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