Experimental Methods in Systems Biology
This course is part of Systems Biology and Biotechnology.
This course cannot be purchased separately - to access the complete learning experience, graded assignments, and earn certificates, you'll need to enroll in the full Systems Biology and Biotechnology Specialization program. You can audit this specific course for free to explore the content, which includes access to course materials and lectures. This allows you to learn at your own pace without any financial commitment.
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What you'll learn
Master RNA sequencing and proteomics techniques
Understand flow and mass cytometry methodologies
Apply live-cell imaging for protein dynamics analysis
Analyze experimental data for quality and content
Integrate multiple datasets with network models
Skills you'll gain
This course includes:
10.2 Hours PreRecorded video
8 assignments
Access on Mobile, Tablet, Desktop
FullTime access
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There are 8 modules in this course
This comprehensive course explores modern experimental techniques used in systems biology research. Students learn about four key technologies: mRNA sequencing, mass spectrometry-based proteomics, flow/mass cytometry, and live-cell imaging. The curriculum covers both theoretical foundations and practical laboratory applications, with emphasis on generating quantitative data for computational modeling. Through hands-on lab demonstrations and data analysis instruction, students gain expertise in techniques ranging from genome-wide studies to single-molecule analysis.
Introduction
Module 1 · 3 Hours to complete
Deep mRNA Sequencing
Module 2 · 2 Hours to complete
Mass Spectrometry-Based Protoeomics
Module 3 · 2 Hours to complete
Midterm Exam
Module 4 · 30 Minutes to complete
Live Cell Imaging
Module 6 · 2 Hours to complete
Network Models and Dynamical Models
Module 7 · 2 Hours to complete
Final Exam
Module 8 · 30 Minutes to complete
Fee Structure
Individual course purchase is not available - to enroll in this course with a certificate, you need to purchase the complete Professional Certificate Course. For enrollment and detailed fee structure, visit the following: Systems Biology and Biotechnology
Instructor
Assistant Professor
Dr. Marc Birtwistle is an Assistant Professor in the Department of Pharmacology and Systems Therapeutics at the Icahn School of Medicine at Mount Sinai, where he also contributes to the Systems Biology Center New York. With a formal background in chemical engineering, Dr. Birtwistle integrates quantitative methods for mathematical modeling with experimental cell and molecular biology to address complex challenges in cancer research. His interdisciplinary approach allows him to explore how variability among individual cells influences signaling pathways and responses to therapies, a critical area in understanding cancer treatment efficacy.Dr. Birtwistle teaches the course Experimental Methods in Systems Biology, which focuses on methodologies essential for studying biological systems through experimental and computational techniques. His research has been published in numerous prestigious journals, and he is involved in several NIH-funded projects aimed at unraveling the mechanisms behind cellular responses to treatments. Through his work, Dr. Birtwistle aims to advance the field of systems biology and pharmacology, ultimately contributing to more effective cancer therapies and personalized medicine strategies
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