Cellular Mechanisms of Brain Function

This course offers a comprehensive exploration of mammalian brain function at the cellular level. It begins with a detailed examination of the fundamental building blocks of the brain: neurons and synapses. Students will gain in-depth knowledge of the biophysical mechanisms underlying electrical signaling in neurons and the complex interactions at synapses. The course then progresses to the study of neuronal networks, with a particular focus on the interplay between excitatory glutamatergic and inhibitory GABAergic neurons. This network-level understanding is then applied to the context of sensory processing, providing insights into how the brain interprets and responds to external stimuli. The course also covers the latest techniques and methods used in studying mammalian brain function in vivo, giving students exposure to cutting-edge neuroscience research practices. Throughout the course, there is a strong emphasis on linking cellular and network mechanisms to observable behaviors, particularly in mice. This approach helps students understand the causal relationships between brain activity and behavior. The course covers topics such as neuronal computations, sensorimotor integration, and learning, providing a well-rounded understanding of brain function from the microscopic to the behavioral level.