Introduction to Industrial Fermentation
Learn the fundamentals of industrial fermentation processes to convert renewable feedstocks into sustainable products using microorganisms.
Learn the fundamentals of industrial fermentation processes to convert renewable feedstocks into sustainable products using microorganisms.
Master the essentials of industrial fermentation processes in this comprehensive course. Explore how renewable feedstocks are transformed into valuable biomaterials, chemicals, nutrition products, and biofuels through microbial processes. Learn to design, optimize, and scale fermentation processes from lab to factory scale. The course combines theoretical foundations with practical applications, including a case study on producing 1,3-propane diol from sugar. Gain insights from industry experts and understand the sustainable value chain of industrial fermentation.
Instructors:
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What you'll learn
Design and quantify industrial-scale fermentation processes
Analyze and optimize microbial growth and product formation
Understand scale-up challenges from laboratory to industrial production
Apply mathematical models for process analysis and improvement
Evaluate sustainability aspects of bioprocess operations
Implement solutions for common fermentation challenges
Skills you'll gain
This course includes:
PreRecorded video
Graded assignments, exams
Access on Mobile, Tablet, Desktop
Limited Access access
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There are 6 modules in this course
The course provides a comprehensive introduction to industrial fermentation processes and their role in sustainable production. Starting with fundamentals of microbial growth and metabolism, it progresses through process design, optimization, and scale-up considerations. Students learn about balances and microbial rates, black box modeling, fermentation design, and scaling principles. The curriculum includes practical case studies and guest lectures from industry experts, offering real-world perspectives on industrial applications. Special attention is given to process sustainability, renewable feedstocks, and common operational challenges.
Industrial Fermentation
Module 1
Balances and Microbial Rates
Module 2
Black Box Model and Process Reaction
Module 3
Fermentation Design
Module 4
Scale-down and Scale-up
Module 5
Wrap-up
Module 6
Fee Structure
Instructors
4 Courses
Sustainable Bioprocess Engineering and Innovation Leader
Henk Noorman currently serves as Head of Sustainability Science & Research at dsm-firmenich, while holding positions as Honorary Professor of Bioprocess Design and Integration at TU Delft and Scientific Director of AI4b.io. His career spans over three decades of expertise in bioprocess technology and sustainable engineering, beginning with his Chemical Engineering degree from Groningen University and PhD in Biotechnology from TU Delft. After coordinating a Nordic research consortium on fermentation scale-up, he joined Gist-brocades and DSM in 1994, where he progressed through various senior scientific roles, including Senior Science Fellow Bioprocess Technology and Corporate Science Fellow Engineering Sciences. His work focuses on advancing open innovation in industrial processes using renewable fuels, particularly in fermentation development, antibiotics production, and biobased chemicals. Through his dual roles in industry and academia, he bridges theoretical research with practical applications, contributing significantly to the bio-based economy. His expertise spans bioprocess design, scale-up optimization, and sustainable biosystems engineering, with extensive experience in managing innovation projects and coordinating private-public partnerships. His research impact is evidenced by over 2,700 citations to his work, establishing him as a leading figure in industrial biotechnology and sustainable bioprocessing.
4 Courses
Expert in Bioprocess Integration and Sustainable Biotechnology
Adrie Straathof serves as an Associate Professor and Section Leader in the Bioprocess Engineering group within TU Delft's Department of Biotechnology. His research focuses on developing novel production processes for chemicals and fuels from biomass and CO2 using microbial and enzymatic conversions. He leads initiatives in bioprocess integration, specializing in in-situ product recovery techniques such as crystallization, adsorption, extraction, and membrane permeation. His work encompasses both experimental and model-based studies aimed at creating economically and environmentally sustainable integrated bioprocesses. As part of the Industrial Biotechnology program, he contributes to advancing sustainable processing methods for biobased products. His expertise extends to the development of circular economy solutions, including innovative technologies for extracting valuable components from waste streams using ion exchange and CO2-expanded alcohol methods. Straathof actively collaborates with industry partners and leads research projects focused on transforming wastewater into polymers and developing sustainable biotechnological manufacturing processes.
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